Bulk 7-Dehydrocholesterol Powder Manufacturer in China
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7-Dehydrocholesterol Bulk Powder (7-DHC)
| Product Name | 7-Dehydrocholesterol Powder |
| Other Names | 7-DHC, Provitamin D3, Cholesta-5,7-dien-3β-ol, (1R,3aR,7S,9aR,9bS,11aR)-9a,11a-Dimethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,6,7,8,9,9a,9b,10,11,11a-dodecahydro-1H-cyclopenta[a]phenanthren-7-ol |
| CAS Number | 434-16-2 |
| Molecular Formula | C27H44O |
| Molecular Weight | 384.64 |
| Specifications | ≥95.0% 7-DHC |
| Appearance / Color | White to Light Yellow Crystalline Powder |
| Bulk Package | 25kg/drum |
| OEM Services | Custom Formulation, Blending, Private Label Packaging, Custom Granulation & Particle Size, Capsules, Tablets, etc. |
Henan Unicorns Biotechnology Co., Ltd. is a leading wholesale 7-Dehydrocholesterol Powder manufacturer in China. We supply bulk 7-DHC to vitamin manufacturers, pharmaceutical companies, nutraceutical ingredient distributors, research suppliers, contract manufacturers, and industrial formulation companies.
Our factory supports an annual production and export capacity of up to 600 tons across this ingredient line. Lanolin-derived and fish-oil-derived options are available based on the buyer’s sourcing needs. Standard material contains at least 95% 7-Dehydrocholesterol and is supplied as a white to light-yellow crystalline powder.
We support custom particle size, packaging, source selection, testing plans, export documents, and OEM bulk packing. Related products include Cholesterol Powder, Vegetarian Cholesterol Powder, Vegetarian 7-Dehydrocholesterol Powder, Bilirubin Powder, Bile Acids Powder, Ox Bile Extract Powder, and Tauroursodeoxycholic Acid Powder.
What Is 7-Dehydrocholesterol?
7-Dehydrocholesterol is a naturally occurring sterol and the direct biological precursor of cholesterol and vitamin D3. It is commonly shortened to 7-DHC and is also known as Provitamin D3.
When exposed to ultraviolet B light, 7-DHC first forms previtamin D3. Heat then converts previtamin D3 into cholecalciferol, which is vitamin D3. This property makes 7-DHC an important raw material for industrial vitamin D3 production.
It is also used in sterol analysis, cholesterol biosynthesis studies, photochemical conversion, and laboratory research.
Sources of 7-Dehydrocholesterol
7-DHC occurs naturally in animal tissues and human skin. It is also present in fish and other animal sterol fractions. However, it is not treated as a common food nutrient.
Commercial 7-Dehydrocholesterol is usually produced from a purified cholesterol feedstock. Lanolin from sheep wool is the best-known industrial source. Fish-oil-derived material is also available for buyers with specific origin requirements.
Unicorns Biotechnology can supply either source according to the approved product specification.
Solubility and Formulation Properties
7-Dehydrocholesterol has very low water solubility because it is a lipophilic sterol. It dissolves more readily in ethanol and selected organic solvents.
The ingredient should be protected from oxygen, heat, and strong light during handling. Its conjugated double-bond structure can oxidize when exposed to unsuitable storage conditions.
7-DHC is mainly an industrial intermediate rather than a finished oral supplement ingredient. Downstream use should be reviewed according to the target market, intended application, stability requirements, and local regulations.
Henan Unicorns Biotechnology supplies wholesale 7-Dehydrocholesterol ingredients with custom particle size, packaging, source, testing requirements, and private-label packing.
7-Dehydrocholesterol Powder Specifications
Unicorns Biotechnology supplies ≥95.0% 7-Dehydrocholesterol Powder as a white to light-yellow crystalline material.
Standard quality limits include loss on drying of no more than 5.0% and total heavy metals below 10 ppm. Lead and arsenic are each limited to 2 ppm, cadmium to 1 ppm, and mercury to 0.1 ppm.
Microbial limits include a total plate count below 1,000 CFU/g and yeast and mold below 100 CFU/g. E. coli and Salmonella must test negative.
Standard packaging is 25 kg per drum. Residual solvent testing by gas chromatography can be added according to the buyer’s requested standard.
Standard 7-DHC Specification Table
| Test Item | Specification | Typical Test Method |
| Identification | Conforms to reference standard | HPLC, IR, or agreed method |
| 7-Dehydrocholesterol Assay | ≥95.0% | HPLC |
| Appearance | White to light-yellow crystalline powder | Visual |
| Loss on Drying | ≤5.0% | Gravimetric |
| Total Heavy Metals | ≤10 ppm | ICP-MS or ICP-OES |
| Arsenic | ≤2 ppm | ICP-MS |
| Lead | ≤2 ppm | ICP-MS |
| Cadmium | ≤1 ppm | ICP-MS |
| Mercury | ≤0.1 ppm | ICP-MS |
| Total Plate Count | ≤1,000 CFU/g | Plate count |
| Yeast and Mold | ≤100 CFU/g | Plate count |
| E. coli | Negative | Microbiological test |
| Salmonella | Negative | Microbiological test |
| Residual Solvents | Meets agreed buyer standard | GC, when requested |
| Particle Size | 80 mesh or customized | Sieve test |
| Source | Lanolin or fish oil | Source documentation |
| Packaging | 25 kg per drum | Inspection |
| Country of Origin | China | Origin documentation |
Each production batch can be supplied with a Certificate of Analysis and MSDS. Third-party testing can cover assay, identity, heavy metals, residual solvents, microbiology, and source verification.
Testing plans can be adjusted to meet the buyer’s internal quality standard and destination-market requirements.
7-Dehydrocholesterol vs Cholesterol vs Vitamin D3
7-Dehydrocholesterol, cholesterol, and vitamin D3 are closely related, but they are not interchangeable.
7-DHC is a sterol intermediate. It can be converted into cholesterol through an enzyme reaction or into vitamin D3 after controlled ultraviolet exposure.
Vitamin D3 is the final secosteroid vitamin used in supplements, fortified foods, feed products, and pharmaceutical preparations.
| Item | 7-Dehydrocholesterol | Cholesterol | Vitamin D3 |
| Common Abbreviation | 7-DHC | Cholesterol | D3 |
| CAS Number | 434-16-2 | 57-88-5 | 67-97-0 |
| Molecular Formula | C27H44O | C27H46O | C27H44O |
| Molecular Weight | 384.64 g/mol | 386.65 g/mol | 384.64 g/mol |
| Compound Type | Sterol | Sterol | Secosteroid vitamin |
| Main Biological Role | Precursor of cholesterol and vitamin D3 | Cell membrane and biosynthetic sterol | Vitamin D nutrient |
| Main Industrial Use | Vitamin D3 intermediate and research material | Pharmaceutical, cosmetic, cell culture, and synthesis uses | Supplements, food, feed, and medicines |
| Response to UVB | Converts toward previtamin D3 | Not the standard direct D3 precursor | Final UV-derived product |
| Finished Supplement Use | Usually not used directly | Limited and application-specific | Commonly used |
| Typical B2B Buyer | Vitamin producer or research supplier | Pharma, cosmetic, and biotech manufacturer | Supplement, food, feed, and pharmaceutical manufacturer |
7-DHC and vitamin D3 share the same molecular formula and molecular weight, but their chemical structures differ.
Ultraviolet exposure opens one of the sterol rings in 7-DHC. This reaction produces the secosteroid structure found in vitamin D3.
Functions and Commercial Benefits of 7-DHC
7-Dehydrocholesterol should not be marketed as a normal finished supplement. Its main value comes from its role as a manufacturing intermediate, biological precursor, analytical material, and research sterol.
Vitamin D3 Precursor
7-DHC is the standard precursor used for vitamin D3 manufacturing. Controlled ultraviolet irradiation converts it into previtamin D3. Thermal conversion then forms cholecalciferol.
High assay, controlled impurities, and stable sourcing help improve conversion consistency and downstream purification.
Defined Sterol Intermediate
A standardized 7-DHC powder gives manufacturers a measured sterol starting material. This supports better control of reaction input, impurity levels, conversion yield, and batch records.
A minimum assay of 95% supports consistent industrial processing and quality checks.
Cholesterol Biosynthesis Research
7-DHC is the immediate biological precursor of cholesterol. Researchers use it to study the DHCR7 enzyme, sterol metabolism, cholesterol pathways, and related biochemical processes.
It can also be used to compare sterol conversion, oxidation, and degradation behavior.
Photochemical and Analytical Use
The conjugated diene structure of 7-DHC responds to ultraviolet light. This makes the material useful in UV conversion studies, photochemical testing, sterol analysis, and analytical method development.
It may also be used as a reference material or internal standard in selected sterol testing methods.
How Is 7-Dehydrocholesterol Powder Manufactured?
Commercial 7-Dehydrocholesterol production starts with a selected sterol source. This is usually lanolin-derived cholesterol or a purified fish-oil sterol fraction.
The raw sterol material is cleaned, separated, and refined to obtain a controlled cholesterol feedstock.
The cholesterol then passes through a chemical conversion process that introduces the required 5,7-diene structure. Reaction temperature, oxygen exposure, solvent quality, and processing time must be closely controlled.
The converted material is separated from side products and unreacted sterols. Recrystallization and further purification raise the 7-DHC assay to at least 95%.
The purified material is dried under controlled conditions, milled or sieved, tested, and packed in light-resistant drums.
Final testing covers identity, assay, moisture, heavy metals, microbiological limits, and other buyer-approved items. Light and oxygen controls are important because 7-DHC can oxidize during processing and storage.
Applications of 7-Dehydrocholesterol Powder
Bulk 7-Dehydrocholesterol Powder is mainly supplied to industrial vitamin producers, pharmaceutical raw-material companies, research laboratories, and analytical suppliers.
Its suitability depends on the assay, origin, impurity profile, storage conditions, and downstream process requirements.
Vitamin D3 Manufacturing
Pharmaceutical and Nutraceutical Intermediate
Analytical Standards and Sterol Testing
Biomedical and Photochemical Research
Storage and Handling of 7-DHC Powder
7-Dehydrocholesterol is sensitive to light, heat, air, and oxidation. Store the powder in tightly sealed and light-resistant packaging.
Keep the material away from moisture, strong oxidizing substances, and direct sunlight.
For long-term storage, follow the batch-specific MSDS and technical data sheet. Low-temperature storage may be required for some grades or long storage periods.
Do not open the drum in direct sunlight. Limit air exposure during sampling and repacking.
Nitrogen protection, cold-chain shipping, or smaller inner packs can be discussed for projects with strict stability requirements.
Where to Buy Bulk 7-Dehydrocholesterol Powder
Henan Unicorns Biotechnology Co., Ltd. is a professional bulk 7-Dehydrocholesterol Powder supplier and factory in China.
We supply high-quality ≥95% 7-DHC for vitamin D3 manufacturing, pharmaceutical processing, analytical testing, and research use.
Buyers can choose lanolin-derived or fish-oil-derived material. We support bulk wholesale orders, custom mesh sizes, private labels, source documents, third-party testing, and export paperwork.
Free samples are available for evaluation before a commercial order.
Why Buy 7-DHC from Unicorns Biotechnology?
| Advantage | What Buyers Receive |
| China Factory Supply | Direct communication, stable production, and factory wholesale pricing |
| Standard Assay | ≥95.0% 7-Dehydrocholesterol |
| Source Options | Lanolin or fish oil |
| Quality Control | Assay, heavy metals, microbial testing, and identity checks |
| Third-Party Testing | Independent reports based on the buyer’s requested test items |
| Custom Specifications | Source, particle size, testing, packing, and inner-pack options |
| Export Documents | COA, MSDS, specification sheet, origin statement, and flow chart |
| Bulk Packaging | Standard 25 kg drums and custom smaller packs |
| OEM Support | Bulk repacking, branded labels, private-label drums, and custom packaging |
| Downstream Support | Raw materials for vitamin D3 capsules, tablets, premixes, and other formats |
| Certificate Review | GMP, Halal, Kosher, allergen, and Non-GMO documents based on source and grade |
| Sample Service | Free evaluation sample before bulk purchase |
| Global Shipment | Export support for supplement, pharmaceutical, research, and ingredient buyers |
Unicorns Biotechnology also supplies cholesterol derivatives, animal extracts, organ powders, bile acids, peptides, and related glandular ingredients.
This helps ingredient distributors and contract manufacturers purchase several raw materials from one supplier.
Contact Unicorns Biotechnology for the latest 7-Dehydrocholesterol wholesale price, free sample, source options, lead time, third-party testing, and custom packaging quotation.
Frequently Asked Questions (FAQs)
Buyers often ask about the relationship between 7-Dehydrocholesterol, cholesterol, and vitamin D3, as well as purity, source, production, testing, storage, and export terms. Unicorns Biotechnology supplies bulk 7-DHC for vitamin D3 manufacturing, sterol research, analytical use, and pharmaceutical processing. We support source selection, custom specifications, third-party testing, bulk packaging, samples, and international shipment.
Frequently Asked Questions (FAQs)
Is 7-Dehydrocholesterol the Same as Cholesterol?
No. 7-Dehydrocholesterol and cholesterol are closely related sterols, but they are different compounds.
7-Dehydrocholesterol has the molecular formula C27H44O and CAS number 434-16-2. Cholesterol has the molecular formula C27H46O and CAS number 57-88-5.
7-DHC is an immediate biological precursor of cholesterol. The enzyme DHCR7 converts 7-DHC into cholesterol by reducing one of its double bonds.
How Is 7-Dehydrocholesterol Related to Vitamin D?
7-Dehydrocholesterol is commonly called Provitamin D3 because it is the direct precursor used to form vitamin D3.
When 7-DHC is exposed to controlled ultraviolet light, it converts into previtamin D3. Heat then changes previtamin D3 into cholecalciferol, also known as vitamin D3.
This reaction makes high-purity 7-DHC an important raw material for industrial vitamin D3 production.
Is 7-Dehydrocholesterol the Same as Vitamin D3?
No. 7-Dehydrocholesterol is the starting sterol, while vitamin D3 is the product formed after ultraviolet and thermal conversion.
Although both compounds have the same molecular formula, their chemical structures are different. 7-DHC should not be described or sold as finished vitamin D3.
What Is 7-Dehydrocholesterol Powder Used For?
The main use of bulk 7-Dehydrocholesterol Powder is vitamin D3 manufacturing. It is also used in cholesterol biosynthesis research, sterol analysis, ultraviolet conversion studies, analytical method development, and pharmaceutical research.
Typical buyers include vitamin manufacturers, pharmaceutical ingredient companies, research laboratories, analytical reagent distributors, and contract manufacturers.
What Sources of 7-Dehydrocholesterol Are Available?
Unicorns Biotechnology can supply 7-DHC made from lanolin-derived sterols or fish-oil-derived sterols.
Lanolin is a common industrial source because it contains cholesterol that can be purified and converted into 7-DHC. Fish-oil-derived material is available for buyers with specific sourcing, labeling, or market requirements.
Please state the required source when requesting a quotation or sample.
Do You Supply Vegetarian 7-Dehydrocholesterol?
Standard 7-DHC made from lanolin or fish oil is animal-derived and should not be labeled vegetarian.
Vegetarian or plant-based alternatives require a different production route and separate source documentation. Buyers looking for vegetarian 7-Dehydrocholesterol should request a source review, specification, and availability confirmation before ordering.
How Is 7-Dehydrocholesterol Manufactured?
Production normally starts with a purified cholesterol or sterol feedstock. The raw material passes through a controlled chemical conversion that forms the required 5,7-diene structure.
The converted material is separated, purified, recrystallized, dried, milled, sieved, tested, and packed. Light, heat, oxygen, reaction time, and solvent quality must be controlled throughout production.
The exact process may vary according to source, purity target, and factory production method.
What Documents Can You Provide?
Available technical and export documents may include:
- Certificate of Analysis
- Material Safety Data Sheet
- Product specification
- Manufacturing flow chart
- Country of origin statement
- Source declaration
- Allergen statement
- Non-GMO statement
- Packing list
- Commercial invoice
- Third-party laboratory report
Halal, Kosher, GMP, and other certificate requests must be reviewed according to the selected source, production line, and current certificate scope.
Can I Request a Free Sample?
Yes. Unicorns Biotechnology can provide a free evaluation sample for qualified B2B projects.
The buyer may need to cover international courier charges. Please provide the intended application, required source, target purity, expected annual demand, and delivery country when requesting a sample.
Do You Offer Custom Specifications?
Yes. Unicorns Biotechnology can review custom requirements for assay, source, particle size, residual solvents, heavy metals, microbiological limits, packaging, inner-pack size, and third-party testing.
Custom specifications must be confirmed before production. The approved specification will be used for production, quality control, and batch release.
Do You Offer OEM or Private-Label Services?
Yes. Our OEM services mainly cover bulk repacking, custom drum labels, private-label packaging, smaller inner packs, source-specific documentation, and buyer-branded export cartons.
Because 7-DHC is mainly an industrial intermediate, it is not normally packed as a direct consumer supplement. Finished vitamin D3 capsules, tablets, softgels, or premixes require separate formulation and regulatory review.
How Is Bulk 7-Dehydrocholesterol Priced?
The wholesale price depends on purity, source, order quantity, packaging, testing requirements, stock status, and shipping terms.
Lanolin-derived and fish-oil-derived grades may have different costs. Added testing, small packaging, cold-chain handling, or custom specifications can also affect the final quotation.
For an accurate price, send us your required quantity, purity, source, destination, and delivery terms.
How Should 7-Dehydrocholesterol Be Stored?
Store 7-DHC in tightly sealed, light-resistant packaging, away from heat, moisture, air, and strong oxidizing substances.
The material is sensitive to light and oxidation. Limit air exposure during sampling and repacking. Low-temperature storage, nitrogen protection, or cold-chain shipment may be recommended for long storage periods or sensitive applications.
Always follow the storage conditions stated on the batch label, specification, and MSDS.
Can You Supply Small Research Quantities?
Yes. Smaller quantities may be available for research laboratories, universities, analytical companies, and pilot-production projects.
Available pack sizes depend on stock, source, assay, and destination. Please provide the required quantity and intended use when requesting a quotation.
Can You Supply Small Research Quantities?
Yes. Smaller quantities may be available for research laboratories, universities, analytical companies, and pilot-production projects.
Available pack sizes depend on stock, source, assay, and destination. Please provide the required quantity and intended use when requesting a quotation.