Bulk Ox Bile Extract Powder Manufacturer in China
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Ox Bile Bulk Powder
| Product Name | Ox Bile Extract Powder |
| Other Names | Ox Bile Powder, Bovine Bile Extract Powder, Bovine Bile Powder, Bovine Bile Extract, Dried Ox Bile Extract, Desiccated Ox Bile, Desiccated Bovine Bile, Ox Bile Concentrate Powder, Standardized Ox Bile Extract, 45% Cholic Acid Ox Bile Powder, Ox Gall Powder |
| Active Ingredient | Cholic Acid |
| CAS Number | 81-25-4 |
| Molecular Formula | C24H40O5 |
| Molecular Weight | 408.57 |
| Specifications | ≥45.0% Cholic Acid |
| Appearance / Color | Yellow powder |
| Applications | Digestive Formulas, Supports the Emulsification of Dietary Fats, Supports Normal Fat Digestion |
| Bulk Package | 25kg/drum |
| OEM Services | Custom Formulation, Blending, Private Label Packaging, Custom Granulation & Particle Size, Capsules, Tablets, etc. |
Unicorns Biotechnology is a wholesale Ox Bile Extract Powder manufacturer in China. We supply standardized bovine bile ingredients to supplement brands, pharmaceutical companies, ingredient distributors, contract manufacturers, private label companies, veterinary nutrition brands and research suppliers.
Our main grade contains not less than 45% cholic acid. Custom grades with a minimum of 25% or 40% cholic acid are also available. Annual manufacturing capacity reaches 700 tons, supporting regular orders, long-term contracts and international distribution.
We provide bulk Ox Bile Powder for capsules, tablets, digestive enzyme blends, veterinary formulas and other approved applications. Custom particle size, packaging, labeling and OEM services are available. We can also supply animal glandular powders, glandular extracts, pancreatin, bile derivatives and other animal-derived ingredients.
What Is Ox Bile?
Ox bile is a digestive fluid produced by the liver of cattle and stored in the gallbladder. It contains bile acids, bile salts, pigments, cholesterol and other natural bile components.
In the digestive system, bile helps disperse dietary fats into smaller droplets. This allows pancreatic lipase and other digestive processes to work more efficiently. Bile also helps the intestine absorb fats and fat-soluble nutrients.
Ox Bile Extract Powder is made by collecting qualified bovine bile, adjusting its pH, filtering it, concentrating it and drying it into a stable powder. The standard product is yellow to brownish-yellow, bitter in taste and readily soluble in water.
Other Names for Ox Bile Extract Powder
Ox Bile Extract Powder is also known as:
Ox Bile Powder, Ox Bile Extract, Bovine Bile Extract Powder, Bovine Bile Powder, Bovine Bile Extract, Dried Ox Bile Extract, Desiccated Ox Bile, Desiccated Bovine Bile, Ox Bile Concentrate Powder, Standardized Ox Bile Extract, 45% Cholic Acid Ox Bile Powder, Ox Gall Powder, Oxgall, Purified Oxgall and Fel Bovis.
The combined name “Ox Bile Extract Powder” is the clearest choice for a standardized, dried bovine bile ingredient. “Ox Bile Powder” is also widely used in supplement and raw-material searches.
Ox Bile Extract CAS Number
Ox bile extract is commonly identified by CAS No. 8008-63-7, which refers to the whole bile extract as a natural mixture of bile acids, bile salts, and other components. This CAS number is correct for ox bile extract as a material, but it does not represent a single pure compound.
Cholic acid, the main standardized marker in our product, is a specific chemical substance with its own CAS number: 81-25-4. This is the correct CAS number when referring to pure cholic acid.
The difference arises because ox bile extract is not a single molecule, while cholic acid is a defined compound. Therefore, both CAS numbers are correct, but they apply to different things:
- 8008-63-7: Ox bile extract (mixture)
- 81-25-4: Cholic acid (pure compound)
For reference, cholic acid has the molecular formula C₂₄H₄₀O₅ and a molecular weight of 408.57 g/mol.
Appearance and Physical Properties
Unicorns Biotechnology’s Ox Bile Extract is supplied as a yellow powder with a strongly bitter taste. It dissolves readily in water and can absorb moisture when exposed to air.
The powder should be stored in a sealed container in a cool, dry place. Standard and custom particle sizes are available. An 80-mesh powder can be supplied when required for capsule, tablet and dry-blend production.
Natural Composition of Ox Bile Extract Powder
Ox bile is a mixture of bile acids and other compounds naturally present in bovine bile. Its exact profile can vary with the raw material, concentration method and selected grade.
Cholic Acid
Cholic acid is the main standardized active marker. Our standard grade contains at least 45.0% cholic acid. Grades standardized to a minimum of 25% or 40% can also be produced.
Cholic acid is a primary bile acid. It takes part in the formation of bile salts and helps create mixed micelles that disperse fats in the intestine.
Conjugated Bile Acids
Non-hydrolyzed ox bile powder may contain bile acids in conjugated forms, including glycocholic and taurocholic acid derivatives. These water-soluble bile components help disperse dietary lipids in an aqueous digestive environment.
Other Bile Acids
Ox bile may also contain smaller amounts of deoxycholic acid and related bovine bile acids. The exact bile-acid profile should be confirmed by the relevant batch test or custom analytical report.
Other Natural Bile Components
Depending on the purification process, the powder may retain bile pigments, cholesterol, phospholipids, mineral salts and other natural constituents. Buyers who require a specific chromatographic profile can request custom testing.
| Component | Description |
|---|---|
| Cholic acid | Main standardized marker, normally ≥45.0% |
| Conjugated bile acids | May include glycocholic and taurocholic acid derivatives |
| Other bile acids | May include deoxycholic acid and related compounds |
| Bile salts | Water-soluble forms involved in fat emulsification |
| Natural minor components | May include pigments, cholesterol, phospholipids and minerals |
Ox Bile Extract Powder Specifications
The standard Unicorns Biotechnology grade contains at least 45.0% cholic acid. It has a moisture limit of 5.0% and total heavy metals below 10 ppm. Lead, arsenic, cadmium and mercury are controlled separately.
Microbial limits include a total plate count below 1,000 CFU/g and yeast and mould below 100 CFU/g. E. coli, Salmonella and Staphylococcus must test negative.
The material is made from grass-fed bovine origin and is specified as non-GMO, non-irradiated, antibiotic-free, BSE-free and allergen-free. Particle size can be adjusted for capsule, tablet, blend or industrial processing.
The standard specification does not list a fixed residual-solvent limit. A residual-solvent panel can be arranged when required by the customer, destination market or finished-product standard.
| Item | Specification |
| Product name | Ox Bile Extract Powder |
| Source | Grass-fed bovine bile |
| Cholic acid | ≥45.0% |
| Custom cholic acid grades | ≥25.0% or ≥40.0% |
| Identification | Positive |
| Appearance | Yellow powder |
| Taste | Bitter |
| Water solubility | Readily soluble |
| Particle size | Customizable |
| Loss on drying | ≤5.0% |
| Total heavy metals | ≤10 ppm |
| Lead | ≤1 ppm |
| Arsenic | ≤1 ppm |
| Cadmium | ≤1 ppm |
| Mercury | ≤0.1 ppm |
| Total plate count | ≤1,000 CFU/g |
| Yeast and mould | ≤100 CFU/g |
| E. coli | Negative |
| Salmonella | Negative |
| Staphylococcus | Negative |
| GMO status | Non-GMO |
| Irradiation | Non-irradiated |
| BSE status | BSE-free |
| Antibiotic status | Antibiotic-free |
| Allergen status | Allergen-free |
| Standard packaging | 25 kg drum or custom packaging |
| Documents | COA, MSDS and supporting quality statements |
Every production batch is checked before release. Third-party testing can be arranged for assay, heavy metals, microbiology, residual solvents or other buyer-specific items.
Ox Bile Benefits in Digestive Formulas
Ox bile is used in supplements because its bile acids help disperse fats. It is not itself a digestive enzyme and should not be described as one.
Finished-product claims and recommended uses must comply with the rules of the destination market.
Supports the Emulsification of Dietary Fats
Bile acids act as natural surfactants. They break large fat droplets into smaller droplets, increasing the surface area available to pancreatic lipase.
Supports Normal Fat Digestion
Ox bile can be included in formulas designed to support the normal digestion of dietary fats. It is often used with lipase, pancreatin or broad-spectrum digestive enzyme blends.
Supports the Absorption of Fat-Soluble Nutrients
Bile acids help form micelles in the small intestine. These structures assist the normal absorption of fatty acids, cholesterol and fat-soluble vitamins.
Complements Digestive Enzyme Formulas
Bile acids and digestive enzymes perform different jobs. Bile disperses fat, while lipase breaks triglycerides into smaller components. This makes ox bile suitable for combined digestive-support products.
Provides a Standardized Source of Bile Acids
A defined cholic acid assay gives formulators better control over raw-material input. Unicorns Biotechnology supplies 25%, 40% and 45% cholic acid grades for different formulation targets.
How Is Ox Bile Extract Powder Made?
Ox Bile Extract Powder is produced through controlled collection, filtration, concentration, drying and quality testing. The goal is to retain the natural bile-acid profile while creating a stable and easy-to-use powder.
Raw Bovine Bile Collection
Fresh bovine bile is collected from qualified animals. Raw-material records, origin documents and BSE controls are reviewed before the bile enters production.
pH Adjustment and Filtration
The liquid bile is adjusted toward a suitable pH and filtered. This stage removes unwanted physical matter and creates a more uniform liquid for concentration.
Concentration
The filtered bile is concentrated under controlled conditions. Process temperature and holding time are managed to reduce damage to heat-sensitive components.
Controlled Drying
The concentrated bile is converted into powder through spray drying or another validated dehydration process. Our standard ox bile powder is produced without a hydrolysis step, helping retain bile acids mainly in their natural conjugated forms.
Milling and Sieving
The dried material is milled and screened to the required particle size. Standard or custom mesh sizes can be selected according to the finished dosage form.
Blending and Batch Testing
The powder is blended for lot uniformity. Each batch is then tested for cholic acid, moisture, heavy metals, microbiology, appearance and identification.
Packing and Storage
Approved powder is packed in sealed, moisture-resistant containers. A 25 kg drum is commonly used for bulk orders, while custom packaging is available for distributors and OEM projects.
Ox Bile Extract Powder Applications
Ox Bile Extract Powder is mainly used in digestive support formulas and animal-derived ingredient products. The selected grade depends on the desired cholic acid level, dosage form and destination-market rules.
Ox Bile Capsules, Tablets and Pills
Digestive Enzymes with Ox Bile
Gallbladder and Post-Cholecystectomy Formulas
Veterinary and Pet Digestive Products
Ox Bile vs TUDCA, Bile Salts, Betaine HCl and Pancreatin
These ingredients are related to digestion, but they are not interchangeable.
| Ingredient | What It Is | Main Formulation Role | Key Difference |
| Ox bile extract | Natural bovine bile mixture containing several bile acids and bile salts | Supports fat emulsification and digestive formulas | A broad, animal-derived bile mixture |
| Bile salts | Salts or conjugated forms of one or more bile acids | Help disperse fats and form micelles | May be isolated, purified or blended |
| TUDCA | Tauroursodeoxycholic acid, one specific conjugated bile acid | Used in specialized bile-acid and research formulas | A defined molecule, not whole ox bile |
| Betaine HCl | Betaine combined with hydrochloric acid | Used in formulas intended to support stomach acidity | Acts in the stomach, not as a bile replacement |
| Pancreatin | Pancreatic extract containing lipase, protease and amylase | Digests fat, protein and carbohydrates | An enzyme mixture, while ox bile is not an enzyme |
Ox Bile vs TUDCA
Ox bile is a natural mixture of bovine bile acids and bile salts. TUDCA is one defined bile acid called tauroursodeoxycholic acid.
They have different compositions and are used in different types of formulas. TUDCA should not be described as the same ingredient or as a direct substitute for complete ox bile extract.
Bile Salts vs Ox Bile
Ox bile naturally contains bile salts, but the terms are not always equal. A bile salts product may contain selected or purified salts. Ox bile extract usually contains a wider mixture of bile components.
The exact assay and bile-acid profile should be reviewed before replacing one ingredient with another.
Betaine HCl vs Ox Bile
Betaine HCl supplies hydrochloric acid for stomach-focused digestive formulas. Ox bile supplies bile acids used mainly in the small intestine for fat emulsification.
They target different parts of digestion. Some formulas contain both, but one is not a substitute for the other.
Pancreatin and Ox Bile
Pancreatin supplies digestive enzymes, mainly lipase, protease and amylase. Ox bile helps disperse dietary fat so lipase can act across a larger surface area.
The two ingredients are often used together in digestive enzyme formulas.
Bile Acid Factors vs Ox Bile
“Bile Acid Factors” is commonly used as a product or branded formula name, not as one fixed raw material. Such products may contain ox bile, purified bile salts or a blend of bile acids.
Formulators should compare the Supplement Facts panel and assay rather than relying only on the product name.
Where to Buy Bulk Ox Bile Extract Powder
Unicorns Biotechnology supplies bulk Ox Bile Extract Powder directly from our factory in China. We work with supplement manufacturers, pharmaceutical companies, veterinary brands, ingredient distributors and private label businesses.
Our standard product contains at least 45% cholic acid. Custom 25% and 40% grades, particle sizes, bulk packaging and OEM dosage forms are available.
| Unicorns Biotechnology Advantage | Details |
| Manufacturing capacity | Up to 700 tons annually |
| Main specification | Cholic acid ≥45.0% |
| Custom specifications | Cholic acid ≥25.0% or ≥40.0% |
| Bovine source | Grass-fed bovine origin |
| Product formats | Bulk powder, capsules and tablets |
| OEM service | Formulation, packaging, labels and private label production |
| Quality control | Assay, heavy metals and microbiological testing |
| Third-party testing | Available according to buyer requirements |
| Technical documents | COA, MSDS, BSE statement and origin documents |
| Samples | Free samples available for qualified B2B projects |
| Packaging | 25 kg drums and custom packaging |
| Supply options | Wholesale orders, distribution contracts and scheduled shipments |
Contact Unicorns Biotechnology for a free sample, current wholesale price, COA, MSDS or custom specification. Please provide your required cholic acid assay, order quantity, particle size, packaging and destination country.
Frequently Asked Questions (FAQs)
Ox Bile Extract Powder buyers often need to confirm the cholic acid assay, bovine source, quality limits, manufacturing documents and suitability for their finished product. Unicorns Biotechnology supplies bulk ox bile powder with 45% cholic acid as the main grade, along with custom specifications, particle sizes, packaging and OEM services. The following answers cover the most common questions from supplement brands, distributors, contract manufacturers and pharmaceutical ingredient buyers.
Frequently Asked Questions (FAQs)
What is ox bile made of?
Ox bile is made from bovine bile. It contains bile acids, bile salts, pigments, cholesterol, phospholipids and minerals. The exact composition depends on the source and production method.
What is desiccated ox bile powder?
Desiccated Ox Bile Powder is bovine bile that has been filtered, concentrated and dried. “Desiccated,” “dried” and “powdered” are often used for the same general physical form.
Is ox bile a digestive enzyme?
No. Ox bile is not an enzyme. Its bile acids help emulsify fats, while enzymes such as lipase chemically break fats into smaller components.
Are bile salts and ox bile the same thing?
Not exactly. Ox bile contains bile salts, but it also contains several bile acids and other natural bile components. A bile salts ingredient may be more purified or narrowly defined.
Is ox bile and TUDCA the same?
No. TUDCA is one specific conjugated bile acid. Ox bile extract is a mixture of several bovine bile acids, bile salts and related components.
Can I take TUDCA and ox bile together?
There is no general recommendation suitable for every person. They can overlap in bile-acid content and may cause unwanted digestive effects. Consumers should ask a healthcare professional before combining them.
Can I take ox bile and digestive enzymes together?
Many commercial digestive formulas combine ox bile with lipase, pancreatin or other enzymes. Consumers with digestive disease, liver disease, bile-duct problems or recent surgery should seek medical advice first.
What is the difference between betaine HCl and ox bile?
Betaine HCl is used to supply acid in the stomach. Ox bile supplies bile acids that act mainly in the small intestine. They support different digestive stages.
What is pancreatin and ox bile used for in the same formula?
Pancreatin provides enzymes that digest fat, protein and starch. Ox bile helps emulsify fat. The combination is used in multi-ingredient digestive support products.
Are ox bile supplements needed after gallbladder removal?
Not everyone needs them. The liver continues to make bile after the gallbladder is removed, but bile flows more continuously into the intestine. A healthcare professional should assess persistent digestive symptoms rather than assuming a supplement is required.
Does ox bile help you lose weight?
Ox bile is not a proven weight-loss supplement. Helping digest dietary fat does not mean that it blocks fat absorption or causes safe weight loss. Weight-loss claims should not be used without suitable evidence and regulatory approval.
What is an alternative to ox bile?
The suitable alternative depends on the formulation goal. Purified bile salts, TUDCA, digestive enzymes and plant-based digestive blends are not exact substitutes. Each has a different composition and function.
What is the difference between ox bile pills and bulk ox bile powder?
Ox bile pills, tablets and capsules are finished consumer products. Bulk Ox Bile Extract Powder is a raw material purchased by manufacturers for further processing and formulation.
Can the cholic acid content be customized?
Yes. The main specification is cholic acid ≥45.0%. Grades containing a minimum of 25% or 40% cholic acid can also be supplied.
Do you provide OEM ox bile supplements?
Yes. OEM options include ox bile capsules, tablets, digestive enzyme blends, bottle packaging, label design and private label production. Final formulas must meet the regulations of the destination market.
Is Ox Bile Extract the same as cholic acid?
No. Ox bile extract is a natural mixture of several bile acids, bile salts and minor bile components. Cholic acid is one defined bile acid and the main standardized marker used to measure our Ox Bile Extract Powder.
Do you use “Cholic Acid” or “Cholic Acids” on the specification?
“Cholic Acid” is correct when stating the assay of the specific compound. “Bile acids” is used when referring to the broader mixture of cholic acid, deoxycholic acid and conjugated bile acids found in ox bile.
What are the CAS numbers for Ox Bile Extract and cholic acid?
Ox Bile Extract is commonly identified by CAS No. 8008-63-7. Pure cholic acid has CAS No. 81-25-4, a molecular formula of C₂₄H₄₀O₅ and a molecular weight of 408.57 g/mol.
What is the source of your Ox Bile Extract Powder?
The material is produced from bovine bile. Our standard specification identifies the source as grass-fed bovine origin. Raw-material origin and BSE-related documents can be supplied for buyer review.
Is the product hydrolyzed?
Our standard Ox Bile Powder is produced without a hydrolysis step. This helps retain a higher proportion of bile acids in their naturally conjugated forms. Buyers requiring a specific bile-acid profile should request an analytical report.